Saravanan Research Group

Saravanan

Research Group

Sustainable

Science

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in Our Hands

Building

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of Matter

Rapid

Screening,

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Faster Results

Bringing

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Into Lab

Driving

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Reaction Chains


Enzyme Catalysis Lab @ SoC

Green – Eco-friendly – Sustainable

What We Do

The main focus of our research group is to study the unique features of enzymes towards synthetically useful chemical transformations. The work is an interdisciplinary research and involves both; organic chemistry & molecular biology. We are keenly interested in the development of multienzymatic cascade by a Systems Biocatalysis Approach for obtaining valuable pharmaceutical precursors (APIs) and fine chemicals. Fine-tuning enzymes for a required process by improving their stability, selectivity and activity through directed evolution and bioinformatic techniques is all part of our work. Our overall aim is to develop enzymatic processes which are green, sustainable and economical at every step.

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About

Latest News

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Congratulations Karishma - Prime Minister's Research Fellow (Dec 2021 Cycle)

Congratulations Dheeraj - Prime Minister's Research Fellow (May 2021 Cycle)

One vacancy is available for the Project Assistant position

PhD vacancies are not currently available

Latest Publications

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Synthesis of Diverse Imidazole and Quinoxaline Derivatives via Iodine-Mediated Cyclization Reactions

Suganbabu Panneerselvam, Elavarasan Selvaraj, Subramaniyan Mannathan, Thangavelu Saravanan, Baburaj Baskar*

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“Excited” Class I Aldolases: EDA Complex Mediated Photo-biocatalytic Enantioselective β-Alkylation of Enals

Sangoji Dheeraj, Shahana Pulikkathodi, Surabhi Odam Valappil, Kuntal Samanta, Thangavelu Saravanan*

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Enantiodivergent Synthesis of Both (R)- and (S)-Heteroaryl Aldols by Rationally Engineered Aldolases

Karishma Naik, Kodru Jeevani, Krishnendu Bar, Thangavelu Saravanan*

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Exploring the Substrate Scope and Catalytic Promiscuity of Nitroreductase-Like Enzymes

Alejandro Prats Luján, Mohammad Faizan Bhat, Thangavelu Saravanan* Gerrit J. Poelarends*

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Evaluating Multienzyme Cascade Routes for Pharmaceutically Relevant Molecules

Karishma Naik, Sangoji Dheeraj, Kodru Jeevani, Thangavelu Saravanan*

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Microbial alcohol dehydrogenases: recent developments and applications in asymmetric synthesis

Anju Chadha* Santosh Kumar Padhi* Selvaraj Stella* Sowmyalakshmi Venkataraman* Thangavelu Saravanan*

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Visible Light Driven Metal-Free Photoredox Catalyzed α-benzylation and α-oxygenation of N-substituted Tetrahydroisoquinolines: Applications to Synthesis of Natural Products

Selvaraj Elavarasan, Jeyaraj Preety, Ramanjulu Abinaya, Dr. Thangavelu Saravanan , Prof. Kalpattu Kuppusamy Balasubramanian, Dr. Nutalapati Venkatramaiah, Dr. Baburaj Baskar*

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Chemo- and Enantioselective Photoenzymatic Ketone Reductions Using a Promiscuous Flavin-dependent Nitroreductase

Alejandro Prats Luján, Mohammad Faizan Bhat, Thangavelu Saravanan* Gerrit J. Poelarends*

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Saravanan Research Group

Saravanan

Research Group

Advancing impactful research in green chemistry, high-throughput screening, and scalable enzymatic applications.

Address

School of Chemistry, University of Hyderabad,
Gachibowli, Hyderabad - 500046,
Telangana, India.

Contact

+91 - 40 - 23134815

tsaravanan@uohyd.ac.in

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